The feature game of the college football weekend kicks off in Eugene.
No. 7 Indiana at No. 3 Oregon, Saturday October 11 at Autzen Stadium, 12:30 p.m. PT. TV on CBS, Brad Nessler, Gary Danielson and Jenny Dell announcers. Radio on the Oregon Sports Network.
Latest line: Oregon -7.5, down from -10.5 at open. Over/under is 55.5. Moneyline is Oregon -280, Indiana +230.
Weather: Fall officially comes to Autzen Stadium as the forecast calls for a high of 58 with some rain likely. Winds minimal, from SW, 6 mph.
Fan color: Duck fans asked to Wear Yellow.
Key stats: Indiana features an explosive, big-play RPO-based offense coupled with a stubborn, blitzing defense. Hoosiers average 47.6 points per game, give up 9.6 points per game, both second in the conference.
They've given up just 3.21 yards a carry and 88 yards a game on the ground. The defense has produced 16 sacks and 49 tackles per loss in their 5-0 start.
Key storylines: Who's a better coach, the hard-nosed, overachieving Cignetti or the amped-up, energized Dan Lanning? What's the measure, talent acquisition and recruiting or getting the most out of the least?
In program history, IU had six wins against Top Ten opponents before their 63-10 mashing of No. 9 Illinois on September 20.
11/6/37: at No. 8 Ohio State, 10-0
11/7/42: at No. 7 Minnesota, 7-0
11/25/67: No. 3 Purdue, 19-14,
12/21/79: vs. No 9 BYU, 38-37 (Holiday Bowl)
10/101987: at No. 9 Ohio State, 31-10
10/24/20: No. 8/7 Penn State, 36-35 OT
The biggest storyline remains the clash of Heisman Trophy candidates and potential No. 1 draft picks at quarterback.
Dante Moore, Fernando Mendoza and LaNorris Sellers are 1A, 1B and 1C in the 2026 NFL draft QB class pic.twitter.com/NWP2ulYjKb
— Mitchell (@CLEKY_) September 21, 2025
Injuries: Indiana starting cornerback D'Angelo Ponds is probable after missing the Iowa game. Evan Stewart, Dillon Gresham and Trey McNutt remain out for the Ducks.
Indiana is 0-46 all-time on the road vs. AP Top 5 teams and seeks their first road win vs. a Top 10 opponent since 1987, when they beat #9 Ohio State. 😬👀🦆 pic.twitter.com/50LJXYGWix
— DuckZone503 (@DuckZone503) October 7, 2025